The lab’s central mission is to elucidate the neural basis of episodic memory and its disorders, with a specific emphasis on cognitive decline in aging and Alzheimer’s disease. To meet this goal, we develop:
- Novel neuropsychological assays to explore memory function and subtle memory impairments;
- Novel high-resolution structural and functional neuroimaging techniques to peer into the brain’s memory systems with unprecedented detail in both animals and humans; and
- Novel computational methods to create MRI-based “composite biomarkers” that allow us to better diagnose or predict disease states.
Here are the research areas currently pursued in the lab. Click on each one for more details.
- Caffeine and memory consolidation
- Information processing in the hippocampus
- Competitive Trace Theory (CTT)
- Modulation of hippocampal memory
- Neurocognitive aging as a model of hippocampal impairment
- Developing biomarkers for preclinical Alzheimer’s disease
- Imaging in animal models of aging and neurological disease
- Neuroimaging methods development